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    zufsp zinc finger containing ubiquitin peptidase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 562478, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zufspprovided by ZNC
    Official Full Name
    zinc finger containing ubiquitin peptidase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070209-211
    See related
    Ensembl:ENSDARG00000059983 AllianceGenome:ZFIN:ZDB-GENE-070209-211
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7145879; zgc:158611
    Summary
    Predicted to enable cysteine-type deubiquitinase activity and metal ion binding activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human ZUP1 (zinc finger containing ubiquitin peptidase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See zufsp in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (32184485..32196774)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (32230455..32242741)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor, class C, group 6, member A Neighboring gene karyopherin alpha 5 (importin alpha 6) Neighboring gene RWD domain containing 1 Neighboring gene calcium homeostasis modulator protein 5-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC158611

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger-containing ubiquitin peptidase 1
    Names
    zinc finger with UFM1-specific peptidase domain
    NP_001076474.2
    XP_005158409.1
    XP_005158410.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083005.2 → NP_001076474.2  zinc finger-containing ubiquitin peptidase 1

      Status: VALIDATED

      Source sequence(s)
      CT027708
      UniProtKB/TrEMBL
      A0A8M1NC71, F1QAX5
      Related
      ENSDARP00000078444.4, ENSDART00000084009.6
      Conserved Domains (2) summary
      pfam05283
      Location:71 → 149
      MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
      pfam07910
      Location:363 → 581
      Peptidase_C78; Peptidase family C78

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      32184485..32196774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005158352.5 → XP_005158409.1  zinc finger-containing ubiquitin peptidase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B5A2
      Conserved Domains (2) summary
      pfam05283
      Location:71 → 149
      MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
      pfam07910
      Location:343 → 561
      Peptidase_C78; Peptidase family C78

    2. XM_005158353.5 → XP_005158410.1  zinc finger-containing ubiquitin peptidase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M2B580
      Conserved Domains (2) summary
      pfam05283
      Location:71 → 149
      MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
      pfam07910
      Location:307 → 525
      Peptidase_C78; Peptidase family C78
    Nucleotide Protein Strain
    Heading Accession and Version

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