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    larp1b La ribonucleoprotein 1B [ Danio rerio (zebrafish) ]

    Gene ID: 568156, updated on 9-Dec-2024

    Summary

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    Official Symbol
    larp1bprovided by ZNC
    Official Full Name
    La ribonucleoprotein 1Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4154
    See related
    Ensembl:ENSDARG00000061169 AllianceGenome:ZFIN:ZDB-GENE-030131-4154
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc76b04; wu:fc76b04
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of translation. Predicted to act upstream of or within mRNA stabilization. Predicted to be active in cytoplasmic stress granule and cytosol. Is expressed in spermatid. Orthologous to human LARP1B (La ribonucleoprotein 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See larp1b in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (26754019..26802809)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (26735123..26784378)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene calmodulin 1a Neighboring gene NRDE-2, necessary for RNA interference, domain containing Neighboring gene progesterone receptor membrane component 2 Neighboring gene acetylserotonin O-methyltransferase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Antisense RNAs during early vertebrate development are divided in groups with distinct features. Pillay S, et al. Genome Res, 2021 Jun. PMID 33795334, Free PMC Article
    2. Single Cell Transcriptome Sequencing of Zebrafish Testis Revealed Novel Spermatogenesis Marker Genes and Stronger Leydig-Germ Cell Paracrine Interactions. Qian P, et al. Front Genet, 2022. PMID 35360857, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA cap binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA stabilization IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    la-related protein 1; la-related protein 1B
    Names
    La ribonucleoprotein domain family, member 1B
    la related protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      26754019..26802809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214598.1 → XP_068070699.1  la-related protein 1B isoform X1

      UniProtKB/TrEMBL
      A0A8M3B2G7

    2. XM_005158557.5 → XP_005158614.1  la-related protein 1B isoform X3

      UniProtKB/TrEMBL
      A0A8M2B4Y8, A0A8M3B2G7
      Conserved Domains (2) summary
      smart00684
      Location:884 → 922
      DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
      cd08034
      Location:325 → 397
      LARP_1_2; La RNA-binding domain proteins similar to La-related proteins 1 and 2

    3. XM_068214600.1 → XP_068070701.1  la-related protein 1B isoform X4

      UniProtKB/TrEMBL
      A0A8M3B2G7

    4. XM_691468.9 → XP_696560.3  la-related protein 1B isoform X5

      UniProtKB/TrEMBL
      A0A8M3B2G7, A0A8N7T839, F1Q931
      Related
      ENSDARP00000007794.7, ENSDART00000025096.10
      Conserved Domains (2) summary
      smart00684
      Location:849 → 887
      DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
      cd08034
      Location:325 → 397
      LARP_1_2; La RNA-binding domain proteins similar to La-related proteins 1 and 2

    5. XM_068214599.1 → XP_068070700.1  la-related protein 1B isoform X2

      UniProtKB/TrEMBL
      A0A8M3B2G7

    6. XM_068214601.1 → XP_068070702.1  la-related protein 1B isoform X6

      UniProtKB/TrEMBL
      A0A8M3B2G7

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394994.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      7653..39457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068218881.1 → XP_068074982.1  la-related protein 1B isoform X7

    2. XM_021473188.2 → XP_021328863.1  la-related protein 1B isoform X8

      UniProtKB/TrEMBL
      A0A8M9PCV0
      Conserved Domains (3) summary
      smart00684
      Location:581 → 619
      DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
      cl02755
      Location:22 → 94
      LAM; LA motif RNA-binding domain
      cl27057
      Location:684 → 808
      ADK; Adenylate kinase

    3. XM_068218882.1 → XP_068074983.1  la-related protein 1B isoform X9

    4. XM_021473189.2 → XP_021328864.1  la-related protein 1B isoform X10

      UniProtKB/TrEMBL
      A0A8M9PVK3
      Conserved Domains (3) summary
      smart00684
      Location:546 → 584
      DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
      cl02755
      Location:22 → 94
      LAM; LA motif RNA-binding domain
      cl27057
      Location:649 → 773
      ADK; Adenylate kinase
    Nucleotide Protein Strain
    Heading Accession and Version

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