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    arl8a ADP-ribosylation factor-like 8A [ Danio rerio (zebrafish) ]

    Gene ID: 567222, updated on 9-Dec-2024

    Summary

    Official Symbol
    arl8aprovided by ZNC
    Official Full Name
    ADP-ribosylation factor-like 8Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5025
    See related
    Ensembl:ENSDARG00000078686 AllianceGenome:ZFIN:ZDB-GENE-030131-5025
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fe25e11; wu:fe25e11; si:ch1073-204j4.2
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in anterograde axonal transport. Predicted to act upstream of or within protein transport. Predicted to be located in late endosome membrane and lysosome. Predicted to be active in lysosomal membrane. Orthologous to human ARL8A (ADP ribosylation factor like GTPase 8A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See arl8a in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (710759..718615, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (673036..680892, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene E74-like factor 3 (ets domain transcription factor, epithelial-specific ) Neighboring gene G protein-coupled receptor 37 like 1a Neighboring gene zgc:162255 Neighboring gene zinc finger protein 76

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in anterograde axonal transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ADP-ribosylation factor-like protein 8A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001200020.1NP_001186949.1  ADP-ribosylation factor-like protein 8A

      See identical proteins and their annotated locations for NP_001186949.1

      Status: VALIDATED

      Source sequence(s)
      CT693669, CU539055, CU855848, EH500770
      UniProtKB/TrEMBL
      A0A8M1NXH5, F8W2P1
      Related
      ENSDARP00000124659.1, ENSDART00000149320.2
      Conserved Domains (1) summary
      cd04159
      Location:22180
      Arl10_like; Arf-like 9 (Arl9) and 10 (Arl10) GTPases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      710759..718615 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)