U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    spsb1 splA/ryanodine receptor domain and SOCS box containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 334190, updated on 9-Dec-2024

    Summary

    Official Symbol
    spsb1provided by ZNC
    Official Full Name
    splA/ryanodine receptor domain and SOCS box containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6122
    See related
    Ensembl:ENSDARG00000056515 AllianceGenome:ZFIN:ZDB-GENE-030131-6122
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi35c01; wu:fi35c01; zgc:114115
    Summary
    Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in brain; gonad; muscle; and otic vesicle. Orthologous to human SPSB1 (splA/ryanodine receptor domain and SOCS box containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See spsb1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (22496423..22523303, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (22569872..22596752, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene P2X purinoceptor 7-like Neighboring gene uncharacterized LOC795083 Neighboring gene RAP1 GTPase activating protein a Neighboring gene uncharacterized LOC108181455 Neighboring gene uncharacterized LOC137489122 Neighboring gene uncharacterized LOC137489123 Neighboring gene microRNA 34a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    SPRY domain-containing SOCS box protein 1
    Names
    ssb-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025460.1NP_001020631.1  SPRY domain-containing SOCS box protein 1

      See identical proteins and their annotated locations for NP_001020631.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097174
      UniProtKB/TrEMBL
      A0A8M1N6V2, Q4V8W1
      Related
      ENSDARP00000073475.3, ENSDART00000079019.4
      Conserved Domains (2) summary
      cd03718
      Location:232273
      SOCS_SSB1_4; SOCS (suppressors of cytokine signaling) box of SSB1 and SSB4 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 and SSB4 has been shown to bind to MET, the receptor ...
      cd12906
      Location:54227
      SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      22496423..22523303 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395146.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      118773..145208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)