nabp1a nucleic acid binding protein 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nabp1aprovided by ZNC
Official Full Name: nucleic acid binding protein 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041212-71
See related: Ensembl:ENSDARG00000004692 AllianceGenome:ZFIN:ZDB-GENE-041212-71
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: nabp1; obfc2a; fc60e10; fi33c08; obfc2aa; wu:fc60e10; wu:fi33c08; zgc:101644
Summary: Predicted to enable single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination; mitotic G2/M transition checkpoint; and response to ionizing radiation. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Predicted to be part of SOSS complex. Orthologous to human NABP1 (nucleic acid binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (24214659..24218741, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (24403744..24407878, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc60e10 (e-PCR)
- UniSTS:189464

fc67g07.x1 (e-PCR)
- UniSTS:194230

fi33c08.x1 (e-PCR)
- UniSTS:197305

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables single-stranded DNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
involved_in double-strand break repair via homologous recombination	IBA Inferred from Biological aspect of Ancestor more info
involved_in double-strand break repair via homologous recombination	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitotic G2/M transition checkpoint	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic G2/M transition checkpoint	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to ionizing radiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to ionizing radiation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of SOSS complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SOSS complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: SOSS complex subunit B2

Names: SOSS-B2; nucleic acid-binding protein 1; oligonucleotide/oligosaccharide-binding fold containing 2A; oligonucleotide/oligosaccharide-binding fold containing 2Aa; oligonucleotide/oligosaccharide-binding fold-containing protein 2A; sensor of single-strand DNA complex subunit B2; sensor of ssDNA subunit B2; single-stranded DNA-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008643.1 → NP_001008643.1 SOSS complex subunit B2

See identical proteins and their annotated locations for NP_001008643.1

Status: PROVISIONAL

Source sequence(s)

BC086713

UniProtKB/Swiss-Prot

Q5PRC7

Related

ENSDARP00000123018.1, ENSDART00000135356.2

Conserved Domains (1) summary

cd04491
Location:23 → 100

SoSSB_OBF; SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007120.7 Reference GRCz11 Primary Assembly

Range

24214659..24218741 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005167556.5 → XP_005167613.1 SOSS complex subunit B2 isoform X1

UniProtKB/TrEMBL

A0A8M2BF14, G1K2E9

Related

ENSDARP00000005126.6, ENSDART00000007914.8

Conserved Domains (1) summary

cd04491
Location:23 → 100

SoSSB_OBF; SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In ...