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    etnppl ethanolamine-phosphate phospho-lyase [ Danio rerio (zebrafish) ]

    Gene ID: 393421, updated on 9-Dec-2024

    Summary

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    Official Symbol
    etnpplprovided by ZNC
    Official Full Name
    ethanolamine-phosphate phospho-lyaseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1133
    See related
    Ensembl:ENSDARG00000035544 AllianceGenome:ZFIN:ZDB-GENE-040426-1133
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    agxt2l1; zgc:63486
    Summary
    Predicted to enable ethanolamine-phosphate phospho-lyase activity. Acts upstream of or within embryonic hemopoiesis. Predicted to be located in mitochondrion. Is expressed in intestinal bulb; liver; and yolk syncytial layer. Orthologous to human ETNPPL (ethanolamine-phosphate phospho-lyase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See etnppl in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (60079239..60090404)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (59774002..59785167)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496229 Neighboring gene collagen type XXV alpha 1 chain Neighboring gene heat shock protein 12B Neighboring gene chaperonin containing TCP1, subunit 7 (eta)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of human hematopoietic stem cell gene expression using zebrafish. Eckfeldt CE, et al. PLoS Biol, 2005 Aug. PMID 16089502, Free PMC Article
    2. The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts. Lang I, et al. Int J Mol Sci, 2020 Aug 9. PMID 32784920, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC63486

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ethanolamine-phosphate phospho-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ethanolamine-phosphate phospho-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryonic hemopoiesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ethanolamine-phosphate phospho-lyase
    Names
    alanine--glyoxylate aminotransferase 2-like 1
    NP_956743.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200449.1 → NP_956743.1  ethanolamine-phosphate phospho-lyase

      See identical proteins and their annotated locations for NP_956743.1

      Status: PROVISIONAL

      Source sequence(s)
      BC055122
      UniProtKB/Swiss-Prot
      Q7SY54
      Related
      ENSDARP00000051523.4, ENSDART00000051524.8
      Conserved Domains (2) summary
      cd00610
      Location:25 → 435
      OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...
      COG0160
      Location:12 → 439
      GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      60079239..60090404
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7SY54.1 GenPept UniProtKB/Swiss-Prot:Q7SY54

    Gene LinkOut

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