gtf2e2 general transcription factor IIE, polypeptide 2, beta [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gtf2e2provided by ZNC
Official Full Name: general transcription factor IIE, polypeptide 2, betaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6794
See related: Ensembl:ENSDARG00000012672 AllianceGenome:ZFIN:ZDB-GENE-030131-6794
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:77074; wu:fa05d01
Summary: Predicted to enable DNA binding activity. Predicted to contribute to TFIIH-class transcription factor complex binding activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIE complex. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 6. Orthologous to human GTF2E2 (general transcription factor IIE subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (22851746..22872274)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (22161007..22181535)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

gtf2e2 (e-PCR), detects polymorphism
- UniSTS:205619

fa01d02.s1 (e-PCR)
- UniSTS:202119

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
contributes_to TFIIH-class transcription factor complex binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in transcription initiation at RNA polymerase II promoter	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIE complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIIE complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: transcription initiation factor IIE subunit beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212731.1 → NP_997896.1 transcription initiation factor IIE subunit beta

See identical proteins and their annotated locations for NP_997896.1

Status: PROVISIONAL

Source sequence(s)

BC067173

UniProtKB/TrEMBL

A0A8M1PI28, Q6NXA3

Related

ENSDARP00000020885.7, ENSDART00000016488.9

Conserved Domains (1) summary

cd07977
Location:67 → 145

TFIIE_beta_winged_helix; TFIIE_beta_winged_helix domain, located at the central core region of TFIIE beta, with double-stranded DNA binding activity