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    gemin8 gem (nuclear organelle) associated protein 8 [ Danio rerio (zebrafish) ]

    Gene ID: 100000842, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gemin8provided by ZNC
    Official Full Name
    gem (nuclear organelle) associated protein 8provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041114-189
    See related
    Ensembl:ENSDARG00000053496 AllianceGenome:ZFIN:ZDB-GENE-041114-189
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92177; wu:fd13g07
    Summary
    Predicted to be involved in spliceosomal snRNP assembly. Predicted to be part of SMN complex. Orthologous to human GEMIN8 (gem nuclear organelle associated protein 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See gemin8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (29058268..29061301, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (28254436..28257489, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490016 Neighboring gene glycoprotein M6Ba Neighboring gene uncharacterized LOC137495507 Neighboring gene cystathionine beta-synthase a Neighboring gene crystallin, alpha A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation. Pei W, et al. NPJ Regen Med, 2020. PMID 32218991, Free PMC Article
    2. Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Iwanami N, et al. Cell Rep, 2016 Nov 22. PMID 27880902, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC92177, MGC158850

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in spliceosomal snRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within spliceosomal snRNP assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SMN complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SMN complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    gem-associated protein 8
    Names
    Gem (nuclear organelle) associated protein 8 like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007317.1 → NP_001007318.1  gem-associated protein 8

      See identical proteins and their annotated locations for NP_001007318.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085647
      UniProtKB/TrEMBL
      Q5U397
      Related
      ENSDARP00000053932.5, ENSDART00000053933.7
      Conserved Domains (1) summary
      pfam15348
      Location:12 → 217
      GEMIN8; Gemini of Cajal bodies-associated protein 8

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      29058268..29061301 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005168381.5 → XP_005168438.1  gem-associated protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BGB9, F1QAZ5
      Related
      ENSDARP00000119143.1, ENSDART00000142350.2
      Conserved Domains (1) summary
      pfam15348
      Location:12 → 217
      GEMIN8; Gemini of Cajal bodies-associated protein 8

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394488.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      142328..145319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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