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    fam168b family with sequence similarity 168 member B [ Danio rerio (zebrafish) ]

    Gene ID: 561051, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fam168bprovided by ZNC
    Official Full Name
    family with sequence similarity 168 member Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-180
    See related
    Ensembl:ENSDARG00000101733 AllianceGenome:ZFIN:ZDB-GENE-060929-180
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb25h10; wu:fb25h10; zgc:153980
    Summary
    Predicted to be located in axon; perinuclear region of cytoplasm; and plasma membrane. Is expressed in brain. Orthologous to human FAM168B (family with sequence similarity 168 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See fam168b in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (31334252..31347202)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (31396998..31409991)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene acid phosphatase 5b, tartrate resistant Neighboring gene ATP-binding cassette, sub-family D (ALD), member 3a Neighboring gene cAMP responsive element modulator b Neighboring gene copine III

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Copper stress induces zebrafish central neural system myelin defects via WNT/NOTCH-hoxb5b signaling and pou3f1/fam168a/fam168b DNA methylation. Zhang T, et al. Biochim Biophys Acta Gene Regul Mech, 2020 Oct. PMID 32745624
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0280, MGC153980

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    myelin-associated neurite-outgrowth inhibitor
    Names
    mani
    protein FAM168B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076569.1 → NP_001070037.1  myelin-associated neurite-outgrowth inhibitor

      See identical proteins and their annotated locations for NP_001070037.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124506
      UniProtKB/Swiss-Prot
      Q08BY2
      Related
      ENSDARP00000136356.1, ENSDART00000172473.2
      Conserved Domains (1) summary
      pfam14944
      Location:1 → 195
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      31334252..31347202
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162851.4 → XP_005162908.1  myelin-associated neurite-outgrowth inhibitor isoform X1

      UniProtKB/TrEMBL
      A0A0R4IF02, A0A8M2B9Y2
      Related
      ENSDARP00000131366.1, ENSDART00000168837.2
      Conserved Domains (1) summary
      pfam14944
      Location:1 → 194
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    2. XM_021470192.2 → XP_021325867.1  myelin-associated neurite-outgrowth inhibitor isoform X2

      UniProtKB/TrEMBL
      A0A8M9P5X8
      Conserved Domains (1) summary
      pfam14944
      Location:1 → 179
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    3. XM_021470193.2 → XP_021325868.1  myelin-associated neurite-outgrowth inhibitor isoform X3

      UniProtKB/TrEMBL
      A0A8M9PG28
      Conserved Domains (1) summary
      pfam14944
      Location:1 → 178
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395182.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      162338..176052
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395367.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      167245..180914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08BY2.1 GenPept UniProtKB/Swiss-Prot:Q08BY2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.