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    mgll monoglyceride lipase [ Danio rerio (zebrafish) ]

    Gene ID: 378960, updated on 9-Dec-2024

    Summary

    Official Symbol
    mgllprovided by ZNC
    Official Full Name
    monoglyceride lipaseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031006-9
    See related
    Ensembl:ENSDARG00000036820 AllianceGenome:ZFIN:ZDB-GENE-031006-9
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb909; zgc:56561; wu:fc66g01
    Summary
    Predicted to enable monoacylglycerol lipase activity. Predicted to be involved in acylglycerol metabolic process. Predicted to be active in membrane. Is expressed in several structures, including EVL; basal plate midbrain region; brain; digestive system; and eye. Orthologous to human MGLL (monoglyceride lipase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mgll in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (26292601..26323849)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (26273462..26304665)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 26 member 6 Neighboring gene solute carrier family 26 member 6 Neighboring gene protein kinase, cAMP-dependent, regulatory, type II, alpha A Neighboring gene hyaluronidase 3 Neighboring gene N-alpha-acetyltransferase 80, NatH catalytic subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC56561

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables monoacylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables monoacylglycerol lipase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in acylglycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    monoglyceride lipase
    NP_956591.1
    XP_068078991.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200297.2NP_956591.1  monoglyceride lipase

      See identical proteins and their annotated locations for NP_956591.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049487
      UniProtKB/TrEMBL
      Q6TGX4, Q7ZWC2
      Related
      ENSDARP00000053462.2, ENSDART00000053463.4
      Conserved Domains (2) summary
      pfam12146
      Location:39275
      Hydrolase_4; Serine aminopeptidase, S33
      cl21494
      Location:22294
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      26292601..26323849
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068222890.1XP_068078991.1  monoglyceride lipase isoform X1