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    thap12a THAP domain containing 12a [ Danio rerio (zebrafish) ]

    Gene ID: 406354, updated on 4-Jan-2025

    Summary

    Official Symbol
    thap12aprovided by ZNC
    Official Full Name
    THAP domain containing 12aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2045
    See related
    Ensembl:ENSDARG00000042489 AllianceGenome:ZFIN:ZDB-GENE-040426-2045
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    prkrir; fb55g11; prkrira; prkrirl; zgc:55697; wu:fb55g11
    Summary
    Predicted to enable DNA binding activity; kinase activity; and metal ion binding activity. Predicted to act upstream of or within phosphorylation. Orthologous to human THAP12 (THAP domain containing 12). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See thap12a in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (32058817..32064405)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (32114957..32120545)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene LHFPL tetraspan subfamily member 6 Neighboring gene si:ch211-266i6.3 Neighboring gene si:dkey-250d21.1 Neighboring gene wingless-type MMTV integration site family, member 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    THAP domain containing 12a
    Names
    protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) a
    protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213081.1NP_998246.1  THAP domain containing 12a

      See identical proteins and their annotated locations for NP_998246.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044456
      UniProtKB/TrEMBL
      Q803J5
      Related
      ENSDARP00000062308.4, ENSDART00000062309.5
      Conserved Domains (2) summary
      pfam05485
      Location:588
      THAP; THAP domain
      pfam14291
      Location:149329
      DUF4371; Domain of unknown function (DUF4371)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      32058817..32064405
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)