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    eif5b eukaryotic translation initiation factor 5B [ Danio rerio (zebrafish) ]

    Gene ID: 561194, updated on 9-Dec-2024

    Summary

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    Official Symbol
    eif5bprovided by ZNC
    Official Full Name
    eukaryotic translation initiation factor 5Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-20
    See related
    Ensembl:ENSDARG00000016548 AllianceGenome:ZFIN:ZDB-GENE-050208-20
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:6912504; si:ch211-254d18.3
    Summary
    Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be active in cytoplasm. Orthologous to human EIF5B (eukaryotic translation initiation factor 5B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See eif5b in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (45925367..45956393)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (45233556..45264600)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene patatin-like phospholipase domain containing 6 Neighboring gene lipoyltransferase 1 Neighboring gene uncharacterized LOC103909161 Neighboring gene Rho guanine nucleotide exchange factor (GEF) 7b Neighboring gene E3 ubiquitin-protein ligase RNF12-B-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Tiling histone H3 lysine 4 and 27 methylation in zebrafish using high-density microarrays. Lindeman LC, et al. PLoS One, 2010 Dec 20. PMID 21187971, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 5B
    XP_001923573.6
    XP_009292016.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      45925367..45956393
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001923538.9 → XP_001923573.6  eukaryotic translation initiation factor 5B isoform X1

      UniProtKB/TrEMBL
      A0A8M1QHW9
      Related
      ENSDARP00000069175.6, ENSDART00000074689.6

    2. XM_009293741.4 → XP_009292016.2  eukaryotic translation initiation factor 5B isoform X2

      UniProtKB/TrEMBL
      A0A8M3AKJ3
    Nucleotide Protein Strain
    Heading Accession and Version

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