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    anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [ Danio rerio (zebrafish) ]

    Gene ID: 322000, updated on 9-Dec-2024

    Summary

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    Official Symbol
    anp32bprovided by ZNC
    Official Full Name
    acidic (leucine-rich) nuclear phosphoprotein 32 family, member Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-719
    See related
    Ensembl:ENSDARG00000023330 AllianceGenome:ZFIN:ZDB-GENE-030131-719
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb908; fa99a11; zgc:77745; wu:fa28c10; wu:fa99a11; wu:fb40e12
    Summary
    Predicted to enable histone binding activity. Predicted to be involved in regulation of apoptotic process. Predicted to be active in nucleus. Is expressed in several structures, including alar plate midbrain region; hematopoietic system; nervous system; optic vesicle; and ventral mesoderm. Orthologous to human ANP32B (acidic nuclear phosphoprotein 32 family member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See anp32b in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (26660356..26664855, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (25966642..25972386, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137494821 Neighboring gene coronin 2Aa Neighboring gene hemogen Neighboring gene tRNA methyltransferase O

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: analysis using transgenic and mutant zebrafish. Peters MJ, et al. Biol Open, 2018 Aug 28. PMID 30097520, Free PMC Article
    2. The Anp32 family of proteins containing leucine-rich repeats. Matilla A, et al. Cerebellum, 2005. PMID 15895553
    3. Comparative analysis of single-cell transcriptomics in human and Zebrafish oocytes. Can H, et al. BMC Genomics, 2020 Jul 8. PMID 32640983, Free PMC Article
    4. Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target. Raman R, et al. Sci Rep, 2021 Jul 27. PMID 34315984, Free PMC Article
    5. High-Resolution Proteomic Profiling Shows Sexual Dimorphism in Zebrafish Heart-Associated Proteins. Niksirat H, et al. J Proteome Res, 2021 Aug 6. PMID 34185526

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    acidic leucine-rich nuclear phosphoprotein 32 family member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212603.2 → NP_997768.2  acidic leucine-rich nuclear phosphoprotein 32 family member B

      Status: VALIDATED

      Source sequence(s)
      BC065856, BI844858, CB365247, CV118158
      UniProtKB/TrEMBL
      A0A8N1Z3N3, F1Q4N7
      Related
      ENSDARP00000093277.3, ENSDART00000102500.5
      Conserved Domains (2) summary
      sd00035
      Location:90 → 114
      LRR_NTF; leucine-rich repeat [structural motif]
      pfam12799
      Location:88 → 130
      LRR_4; Leucine Rich repeats (2 copies)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      26660356..26664855 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159865.5 → XP_005159922.1  acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1

      UniProtKB/TrEMBL
      A0A8M2B6P3
      Conserved Domains (2) summary
      sd00035
      Location:90 → 114
      LRR_NTF; leucine-rich repeat [structural motif]
      pfam12799
      Location:88 → 130
      LRR_4; Leucine Rich repeats (2 copies)
    Nucleotide Protein Strain
    Heading Accession and Version

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