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    nufip2 nuclear FMR1 interacting protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 492366, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nufip2provided by ZNC
    Official Full Name
    nuclear FMR1 interacting protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041111-7
    See related
    Ensembl:ENSDARG00000069066 AllianceGenome:ZFIN:ZDB-GENE-041111-7
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7136583
    Summary
    Predicted to enable RNA binding activity. Predicted to be active in cytoplasmic stress granule and nucleoplasm. Orthologous to human NUFIP2 (nuclear FMR1 interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See nufip2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (30127315..30137780)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (30246222..30257039)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene sialate:O-sulfotransferase 1 Neighboring gene class A basic helix-loop-helix protein 9-like Neighboring gene uncharacterized LOC137487766 Neighboring gene nemo-like kinase, type 2 Neighboring gene LYR motif containing 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of the tbx6/16 subfamily genes in vertebrates: insights from zebrafish. Ahn D, et al. Mol Biol Evol, 2012 Dec. PMID 22915831
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasmic stress granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    FMR1-interacting protein NUFIP2; nuclear FMR1 interacting protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      30127315..30137780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002664642.6 → XP_002664688.1  FMR1-interacting protein NUFIP2

      UniProtKB/TrEMBL
      A0A8M1RRG3, E7FCK6
      Related
      ENSDARP00000090987.3, ENSDART00000100214.5
      Conserved Domains (1) summary
      pfam15293
      Location:45 → 630
      NUFIP2; Nuclear fragile X mental retardation-interacting protein 2
    Nucleotide Protein Strain
    Heading Accession and Version

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