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    plpp5 phospholipid phosphatase 5 [ Danio rerio (zebrafish) ]

    Gene ID: 431758, updated on 9-Dec-2024

    Summary

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    Official Symbol
    plpp5provided by ZNC
    Official Full Name
    phospholipid phosphatase 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040704-54
    See related
    Ensembl:ENSDARG00000057672 AllianceGenome:ZFIN:ZDB-GENE-040704-54
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc49c04; ppapdc1b; zgc:92365; wu:fc49c04
    Summary
    Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation and phospholipid metabolic process. Predicted to be active in membrane. Orthologous to human PLPP5 (phospholipid phosphatase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See plpp5 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (20527427..20537035, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (20570046..20579765, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene transforming, acidic coiled-coil containing protein 1 Neighboring gene uncharacterized LOC137496580 Neighboring gene DDHD domain containing 2 Neighboring gene nuclear receptor binding SET domain protein 3 Neighboring gene leucine zipper-EF-hand containing transmembrane protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification and expression of liver-specific genes after LPS challenge in amphioxus: the hepatic cecum as liver-like organ and "pre-hepatic" acute phase response. Wang Y, et al. Funct Integr Genomics, 2011 Mar. PMID 21052758
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables phosphatidate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phospholipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phospholipid phosphatase 5
    Names
    phosphatidic acid phosphatase type 2 domain containing 1B
    NP_001002211.1
    NP_001417792.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002211.2 → NP_001002211.1  phospholipid phosphatase 5

      See identical proteins and their annotated locations for NP_001002211.1

      Status: VALIDATED

      Source sequence(s)
      BX294119
      UniProtKB/TrEMBL
      Q6GMH7
      Related
      ENSDARP00000064602.4, ENSDART00000064603.6
      Conserved Domains (1) summary
      cd03390
      Location:42 → 230
      PAP2_containing_1_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both ...

    2. NM_001430863.1 → NP_001417792.1  phospholipid phosphatase 5

      Status: VALIDATED

      Source sequence(s)
      BX294119
      UniProtKB/TrEMBL
      Q6GMH7
      Related
      ENSDARP00000116112.1, ENSDART00000135341.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      20527427..20537035 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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