fbxl4 F-box and leucine-rich repeat protein 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fbxl4provided by ZNC
Official Full Name: F-box and leucine-rich repeat protein 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-187
See related: Ensembl:ENSDARG00000026941 AllianceGenome:ZFIN:ZDB-GENE-041114-187
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92297
Summary: Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Used to study mitochondrial DNA depletion syndrome 13. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 13. Orthologous to human FBXL4 (F-box and leucine rich repeat protein 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (32566215..32582805, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (32612188..32628757, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fk93h08.x1 (e-PCR)
- UniSTS:201750

G47247 (e-PCR)
- UniSTS:108030

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of SCF ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: F-box/LRR-repeat protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.