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    aven apoptosis, caspase activation inhibitor [ Danio rerio (zebrafish) ]

    Gene ID: 692323, updated on 9-Dec-2024

    Summary

    Official Symbol
    avenprovided by ZNC
    Official Full Name
    apoptosis, caspase activation inhibitorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041001-171
    See related
    Ensembl:ENSDARG00000002894 AllianceGenome:ZFIN:ZDB-GENE-041001-171
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fc08c09; zgc:136239; si:ch211-150c22.4
    Summary
    Predicted to be involved in negative regulation of G2/M transition of mitotic cell cycle. Orthologous to human AVEN (apoptosis and caspase activation inhibitor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See aven in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (29231532..29269362)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (29328632..29366483)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene katanin p80 subunit B-like 1 Neighboring gene ER membrane protein complex subunit 7b Neighboring gene cholinergic receptor, muscarinic 5b Neighboring gene ryanodine receptor 3 Neighboring gene formin 1 Neighboring gene gremlin 1a, DAN family BMP antagonist

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045292.2 → NP_001038757.2  cell death regulator Aven

      Status: VALIDATED

      Source sequence(s)
      BC116469, BX682544, BX784394, CF348100
      UniProtKB/TrEMBL
      A0A8N1TQ86, F1R220, Q1JQ64
      Related
      ENSDARP00000010975.7, ENSDART00000019759.9

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      29231532..29269362
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005160759.5 → XP_005160816.1  cell death regulator Aven isoform X1

      UniProtKB/TrEMBL
      A0A8M2B7P7, Q1JQ64
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