gpx8 glutathione peroxidase 8 (putative) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gpx8provided by ZNC
Official Full Name: glutathione peroxidase 8 (putative)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-965
See related: Ensembl:ENSDARG00000013302 AllianceGenome:ZFIN:ZDB-GENE-040426-965
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56280
Summary: Predicted to enable peroxidase activity. Predicted to act upstream of or within response to oxidative stress. Predicted to be located in membrane. Is expressed in notochord; otic vesicle; and pharyngeal arch 3-7 skeleton. Orthologous to human GPX8 (glutathione peroxidase 8 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (40177731..40183177, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (40143957..40149403, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables glutathione peroxidase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables peroxidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peroxidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to oxidative stress	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: probable glutathione peroxidase 8

Names: GPx-8; GSHPx-8

NP_956516.1

EC 1.11.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200222.1 → NP_956516.1 probable glutathione peroxidase 8

See identical proteins and their annotated locations for NP_956516.1

Status: PROVISIONAL

Source sequence(s)

BC046044

UniProtKB/Swiss-Prot

Q7ZV14

Related

ENSDARP00000011955.7, ENSDART00000005118.9

Conserved Domains (1) summary

cl00388
Location:47 → 199

Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold