ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: aceprovided by ZNC
Official Full Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-1826
See related: Ensembl:ENSDARG00000079166 AllianceGenome:ZFIN:ZDB-GENE-030131-1826
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb81h03; wu:fb81h03; si:ch211-124e16.1
Summary: Predicted to enable metallopeptidase activity and peptidyl-dipeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adaxial cell; digestive system; eye; heart; and kidney. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); heart valve disease (multiple); and lung disease (multiple). Orthologous to human ACE (angiotensin I converting enzyme). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (5530241..5582060)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (5495208..5547103)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables carboxypeptidase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables metallopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables metallopeptidase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info
enables peptidyl-dipeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peptidyl-dipeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

XP_694336.5

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The following sections contain reference sequences that belong to a specific genome build. Explain