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    ankrd46b ankyrin repeat domain 46b [ Danio rerio (zebrafish) ]

    Gene ID: 402888, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ankrd46bprovided by ZNC
    Official Full Name
    ankyrin repeat domain 46bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050114-7
    See related
    Ensembl:ENSDARG00000015780 AllianceGenome:ZFIN:ZDB-GENE-050114-7
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ankrd46; wu:fq41d11; zgc:109722
    Summary
    Predicted to be located in membrane. Is expressed in central nervous system. Orthologous to human ANKRD46 (ankyrin repeat domain 46). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ankrd46b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (50910954..50917255, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (50635889..50642194, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496217 Neighboring gene procollagen C-endopeptidase enhancer b Neighboring gene progestin and adipoQ receptor family member 9 Neighboring gene collagen, type IV, alpha 6 Neighboring gene collagen, type IV, alpha 5 (Alport syndrome)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish. Yuan JM, et al. J Virol, 2015 Jan. PMID 25355883, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 46
    Names
    ankyrin repeat domain 46

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205596.1 → NP_991159.1  ankyrin repeat domain-containing protein 46

      See identical proteins and their annotated locations for NP_991159.1

      Status: PROVISIONAL

      Source sequence(s)
      AY391435
      UniProtKB/Swiss-Prot
      Q504K9, Q6TNT2
      Related
      ENSDARP00000133092.1, ENSDART00000160398.2
      Conserved Domains (3) summary
      cd00204
      Location:15 → 128
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:16 → 105
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:15 → 42
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      50910954..50917255 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005166503.4 → XP_005166560.1  ankyrin repeat domain-containing protein 46 isoform X1

      See identical proteins and their annotated locations for XP_005166560.1

      UniProtKB/Swiss-Prot
      Q504K9, Q6TNT2
      Related
      ENSDARP00000020125.8, ENSDART00000022918.11
      Conserved Domains (3) summary
      cd00204
      Location:15 → 128
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:16 → 105
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:15 → 42
      ANK; ANK repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6TNT2.1 GenPept UniProtKB/Swiss-Prot:Q6TNT2

    Gene LinkOut

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