afg1la AFG1 like ATPase a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: afg1laprovided by ZNC
Official Full Name: AFG1 like ATPase aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-091006-2
See related: Ensembl:ENSDARG00000011466 AllianceGenome:ZFIN:ZDB-GENE-091006-2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: lace1a
Summary: Predicted to enable ATP hydrolysis activity. Predicted to be active in mitochondrion. Orthologous to human AFG1L (AFG1 like ATPase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (6765629..6789536)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (6608399..6632306)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: AFG1 like ATPase a

Names: lactation elevated 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199767.1 → NP_001186696.1 AFG1 like ATPase a

Status: VALIDATED

Source sequence(s)

CR352340

UniProtKB/TrEMBL

A0A8M1NXE9, X1WDT8

Related

ENSDARP00000128387.1, ENSDART00000156637.3

Conserved Domains (2) summary

COG1485
Location:64 → 462

YhcM; Predicted ATPase [General function prediction only]

cl21455
Location:64 → 462

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases