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    tmem178a transmembrane protein 178a [ Danio rerio (zebrafish) ]

    Gene ID: 767702, updated on 9-Dec-2024

    Summary

    Official Symbol
    tmem178aprovided by ZNC
    Official Full Name
    transmembrane protein 178aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-756
    See related
    Ensembl:ENSDARG00000020758 AllianceGenome:ZFIN:ZDB-GENE-060929-756
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tmem178; zgc:153181
    Summary
    Predicted to be involved in negative regulation of osteoclast differentiation and regulation of cytosolic calcium ion concentration. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in lateral line ganglion. Orthologous to human TMEM178A (transmembrane protein 178A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tmem178a in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (30513790..30531095)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (30266606..30283911)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase 3a Neighboring gene uncharacterized LOC137496710 Neighboring gene peroxisomal trans-2-enoyl-CoA reductase Neighboring gene solute carrier family 8 member 1a Neighboring gene mal, T cell differentiation protein a, tandem duplicate 1 Neighboring gene mal, T cell differentiation protein a, tandem duplicate 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC153181

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of osteoclast differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of osteoclast differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of cytosolic calcium ion concentration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 178A
    Names
    transmembrane protein 178

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076640.1NP_001070108.1  transmembrane protein 178A precursor

      See identical proteins and their annotated locations for NP_001070108.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124270
      UniProtKB/Swiss-Prot
      Q08CE6
      Related
      ENSDARP00000027372.8, ENSDART00000008594.10
      Conserved Domains (1) summary
      cl21598
      Location:110276
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      30513790..30531095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)