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    haus4 HAUS augmin-like complex, subunit 4 [ Danio rerio (zebrafish) ]

    Gene ID: 436698, updated on 9-Dec-2024

    Summary

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    Official Symbol
    haus4provided by ZNC
    Official Full Name
    HAUS augmin-like complex, subunit 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-122
    See related
    Ensembl:ENSDARG00000016594 AllianceGenome:ZFIN:ZDB-GENE-040718-122
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92661
    Summary
    Predicted to enable microtubule minus-end binding activity. Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be part of HAUS complex. Is expressed in proliferative region. Orthologous to human HAUS4 (HAUS augmin like complex subunit 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See haus4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (1493878..1515345)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (1439488..1460905)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene dynamin 1a Neighboring gene uncharacterized LOC137495542 Neighboring gene microRNA 199-1a Neighboring gene golgin A2 Neighboring gene myotubularin-related protein 3 Neighboring gene DDRGK domain containing 1 Neighboring gene cut-like homeobox 2a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface. Hunter MV, et al. Nat Commun, 2021 Nov 1. PMID 34725363, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within centrosome cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within spindle assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of HAUS complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    HAUS augmin-like complex subunit 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002425.1 → NP_001002425.1  HAUS augmin-like complex subunit 4

      See identical proteins and their annotated locations for NP_001002425.1

      Status: PROVISIONAL

      Source sequence(s)
      BC076145
      UniProtKB/TrEMBL
      Q6DH37
      Related
      ENSDARP00000004325.6, ENSDART00000022132.9
      Conserved Domains (1) summary
      pfam14735
      Location:130 → 363
      HAUS4; HAUS augmin-like complex subunit 4

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      1493878..1515345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476069.2 → XP_021331744.1  HAUS augmin-like complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q325
      Conserved Domains (1) summary
      pfam14735
      Location:133 → 366
      HAUS4; HAUS augmin-like complex subunit 4
    Nucleotide Protein Strain
    Heading Accession and Version

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