eif4e2rs1 eukaryotic translation initiation factor 4E family member 2 related sequence 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eif4e2rs1provided by ZNC
Official Full Name: eukaryotic translation initiation factor 4E family member 2 related sequence 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1728
See related: Ensembl:ENSDARG00000015835 AllianceGenome:ZFIN:ZDB-GENE-040426-1728
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: eIF4E2B; zgc:73242
Summary: Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (44427932..44440737)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (44622528..44635333)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA 7-methylguanosine cap binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info
involved_in translational initiation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 4F complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: eukaryotic translation initiation factor 4E family member 2 related sequence 1

Names: eif4E-2B; eukaryotic translation initiation factor 4E class II 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200759.2 → NP_957053.1 eukaryotic translation initiation factor 4E family member 2 related sequence 1

See identical proteins and their annotated locations for NP_957053.1

Status: VALIDATED

Source sequence(s)

CABZ01118710, EH485715, FO904893

UniProtKB/TrEMBL

Q6PBU4, U3RD49

Related

ENSDARP00000132205.1, ENSDART00000160207.3

Conserved Domains (1) summary

pfam01652
Location:52 → 208

IF4E; Eukaryotic initiation factor 4E

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007134.7 Reference GRCz11 Primary Assembly

Range

44427932..44440737

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017353532.3 → XP_017209021.1 eukaryotic translation initiation factor 4E family member 2 related sequence 1 isoform X1

UniProtKB/TrEMBL

A0A8M6YXN8