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    hnrnpd heterogeneous nuclear ribonucleoprotein D [ Danio rerio (zebrafish) ]

    Gene ID: 560522, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hnrnpdprovided by ZNC
    Official Full Name
    heterogeneous nuclear ribonucleoprotein Dprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070424-97
    See related
    Ensembl:ENSDARG00000059246 AllianceGenome:ZFIN:ZDB-GENE-070424-97
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fa28b06; zgc:162951
    Summary
    Enables mRNA 3'-UTR binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in chromatin. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Orthologous to human HNRNPD (heterogeneous nuclear ribonucleoprotein D). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See hnrnpd in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (5000623..5017022, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (5000319..5016737, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene methionine adenosyltransferase II, alpha-like Neighboring gene si:ch73-234b20.5 Neighboring gene heterogeneous nuclear ribonucleoprotein D-like Neighboring gene enolase-phosphatase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1. Poganik JR, et al. FASEB J, 2019 Dec. PMID 31665914, Free PMC Article
    2. Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish. Vejnar CE, et al. Genome Res, 2019 Jul. PMID 31227602, Free PMC Article
    3. An evolutionary approach to recover genes predominantly expressed in the testes of the zebrafish, chicken and mouse. Fouchécourt S, et al. BMC Evol Biol, 2019 Jul 3. PMID 31269894, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA 3'-UTR binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of macromolecule biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of RNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    heterogeneous nuclear ribonucleoprotein D0

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110460.1 → NP_001103930.1  heterogeneous nuclear ribonucleoprotein D0

      See identical proteins and their annotated locations for NP_001103930.1

      Status: PROVISIONAL

      Source sequence(s)
      BC139674
      UniProtKB/TrEMBL
      A4QP67
      Related
      ENSDARP00000092188.3, ENSDART00000101414.4
      Conserved Domains (3) summary
      cd12575
      Location:56 → 129
      RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
      cd12583
      Location:140 → 214
      RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
      pfam08143
      Location:3 → 54
      CBFNT; CBFNT (NUC161) domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      5000623..5017022 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005155547.4 → XP_005155604.1  heterogeneous nuclear ribonucleoprotein D0 isoform X2

      See identical proteins and their annotated locations for XP_005155604.1

      UniProtKB/TrEMBL
      A0A2R8QHK1, A0A8M9QC46
      Conserved Domains (3) summary
      cd12575
      Location:56 → 129
      RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
      cd12583
      Location:140 → 214
      RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
      pfam08143
      Location:3 → 54
      CBFNT; CBFNT (NUC161) domain

    2. XM_005155545.4 → XP_005155602.1  heterogeneous nuclear ribonucleoprotein D0 isoform X1

      See identical proteins and their annotated locations for XP_005155602.1

      UniProtKB/TrEMBL
      A0A8M2B1M3, F1Q8A5
      Conserved Domains (3) summary
      cd12575
      Location:56 → 129
      RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
      cd12583
      Location:140 → 214
      RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
      pfam08143
      Location:3 → 54
      CBFNT; CBFNT (NUC161) domain

    3. XM_021479184.2 → XP_021334859.1  heterogeneous nuclear ribonucleoprotein D0 isoform X2

      UniProtKB/TrEMBL
      A0A2R8QHK1, A0A8M9QC46
      Conserved Domains (3) summary
      cd12575
      Location:56 → 129
      RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
      cd12583
      Location:140 → 214
      RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
      pfam08143
      Location:3 → 54
      CBFNT; CBFNT (NUC161) domain

    4. XM_005155546.4 → XP_005155603.1  heterogeneous nuclear ribonucleoprotein D0 isoform X2

      See identical proteins and their annotated locations for XP_005155603.1

      UniProtKB/TrEMBL
      A0A2R8QHK1, A0A8M9QC46
      Related
      ENSDARP00000153486.1, ENSDART00000191857.1
      Conserved Domains (3) summary
      cd12575
      Location:56 → 129
      RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
      cd12583
      Location:140 → 214
      RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
      pfam08143
      Location:3 → 54
      CBFNT; CBFNT (NUC161) domain

    5. XM_005155544.4 → XP_005155601.1  heterogeneous nuclear ribonucleoprotein D0 isoform X1

      See identical proteins and their annotated locations for XP_005155601.1

      UniProtKB/TrEMBL
      A0A8M2B1M3, F1Q8A5
      Conserved Domains (3) summary
      cd12575
      Location:56 → 129
      RRM1_hnRNPD_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP D0, hnRNP A/B, hnRNP DL and similar proteins
      cd12583
      Location:140 → 214
      RRM2_hnRNPD; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) and similar proteins
      pfam08143
      Location:3 → 54
      CBFNT; CBFNT (NUC161) domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394763.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      54967..71417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395286.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      48463..64909 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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