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    stk38l serine/threonine kinase 38 like [ Danio rerio (zebrafish) ]

    Gene ID: 393957, updated on 9-Dec-2024

    Summary

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    Official Symbol
    stk38lprovided by ZNC
    Official Full Name
    serine/threonine kinase 38 likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-798
    See related
    Ensembl:ENSDARG00000045482 AllianceGenome:ZFIN:ZDB-GENE-040426-798
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55777
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation. Is expressed in several structures, including adaxial cell; intestinal bulb primordium; liver and biliary system; olfactory system; and yolk syncytial layer. Orthologous to human STK38L (serine/threonine kinase 38 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See stk38l in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (20223045..20235939, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (20502393..20514965, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 146 Neighboring gene uncharacterized LOC101883422 Neighboring gene fibrinogen-like 2a Neighboring gene gamma-secretase activating protein Neighboring gene calcium channel, voltage-dependent, alpha 2/delta subunit 4a Neighboring gene leucine-rich repeats and transmembrane domains 2a Neighboring gene calcium channel, voltage-dependent, L type, alpha 1C subunit Neighboring gene decapping mRNA 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. Mayrhofer M, et al. Dis Model Mech, 2017 Jan 1. PMID 27935819, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC55777

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein kinase 38-like
    NP_957276.1
    XP_005164924.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200982.1 → NP_957276.1  serine/threonine-protein kinase 38-like

      See identical proteins and their annotated locations for NP_957276.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044485
      UniProtKB/TrEMBL
      B2GS18, Q803H3
      Related
      ENSDARP00000149794.1, ENSDART00000193655.1
      Conserved Domains (2) summary
      smart00220
      Location:90 → 383
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05627
      Location:87 → 451
      STKc_NDR2; Catalytic domain of the Serine/Threonine Kinase, Nuclear Dbf2-Related kinase 2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      20223045..20235939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005164867.5 → XP_005164924.1  serine/threonine-protein kinase 38-like isoform X1

      UniProtKB/TrEMBL
      A0A8M2BC23, Q5RH05
      Related
      ENSDARP00000119740.1, ENSDART00000146621.2
      Conserved Domains (2) summary
      smart00220
      Location:90 → 383
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05627
      Location:87 → 452
      STKc_NDR2; Catalytic domain of the Serine/Threonine Kinase, Nuclear Dbf2-Related kinase 2
    Nucleotide Protein Strain
    Heading Accession and Version

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