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    lypla1 lysophospholipase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 550279, updated on 9-Dec-2024

    Summary

    Official Symbol
    lypla1provided by ZNC
    Official Full Name
    lysophospholipase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-87
    See related
    Ensembl:ENSDARG00000104228 AllianceGenome:ZFIN:ZDB-GENE-050417-87
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:110260
    Summary
    Predicted to enable carboxylic ester hydrolase activity and palmitoyl-(protein) hydrolase activity. Predicted to be involved in protein depalmitoylation. Predicted to be located in endoplasmic reticulum; nuclear membrane; and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human LYPLA1 (lysophospholipase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    NEW
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    Genomic context

    See lypla1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (58843700..58851774)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (58541270..58549344)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene SRY-box transcription factor 32 Neighboring gene mitochondrial ribosomal protein L15 Neighboring gene mannose receptor, C type 1a Neighboring gene uncharacterized LOC110439951 Neighboring gene uncharacterized LOC110439952

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables carboxylic ester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables palmitoyl-(protein) hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables palmitoyl-(protein) hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    acyl-protein thioesterase 1
    Names
    lysophospholipase I
    NP_001017616.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017616.1NP_001017616.1  acyl-protein thioesterase 1

      See identical proteins and their annotated locations for NP_001017616.1

      Status: PROVISIONAL

      Source sequence(s)
      BC092832
      UniProtKB/TrEMBL
      B2GTL2, Q568J5
      Related
      ENSDARP00000140885.1, ENSDART00000159500.2
      Conserved Domains (1) summary
      pfam02230
      Location:11189
      Abhydrolase_2; Phospholipase/Carboxylesterase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      58843700..58851774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)