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    gpn1 GPN-loop GTPase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 445239, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gpn1provided by ZNC
    Official Full Name
    GPN-loop GTPase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-154
    See related
    Ensembl:ENSDARG00000043928 AllianceGenome:ZFIN:ZDB-GENE-040801-154
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:100927
    Summary
    Predicted to enable GTPase activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human GPN1 (GPN-loop GTPase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See gpn1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (12658435..12675267)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (12504369..12521201)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene zinc finger CCHC domain-containing protein 18-like Neighboring gene elastin microfibril interfacer 1b Neighboring gene uncharacterized LOC101886086 Neighboring gene stathmin-like 4, like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GPN-loop GTPase 1
    NP_001003633.1
    XP_068070489.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003633.1 → NP_001003633.1  GPN-loop GTPase 1

      See identical proteins and their annotated locations for NP_001003633.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078195
      UniProtKB/TrEMBL
      Q6DC83
      Related
      ENSDARP00000121489.1, ENSDART00000139918.2
      Conserved Domains (2) summary
      COG1100
      Location:1 → 203
      Gem1; GTPase SAR1 family domain [General function prediction only]
      pfam03029
      Location:1 → 239
      ATP_bind_1; Conserved hypothetical ATP binding protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      12658435..12675267
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214388.1 → XP_068070489.1  GPN-loop GTPase 1 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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