ppp1r14aa protein phosphatase 1, regulatory (inhibitor) subunit 14Aa [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ppp1r14aaprovided by ZNC
Official Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 14Aaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-413
See related: Ensembl:ENSDARG00000011239 AllianceGenome:ZFIN:ZDB-GENE-050417-413
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: CPI-17; ppp1r14a; im:7147597; zgc:110700
Summary: Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to act upstream of or within regulation of phosphorylation. Predicted to be located in cytoplasm. Is expressed in gut; hindbrain; lateral line nerve; spinal cord; and swim bladder. Orthologous to human PPP1R14A (protein phosphatase 1 regulatory inhibitor subunit 14A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 5

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (36730727..36739509)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (36130574..36139356)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Hoxb1b is likely to directly regulate ppp1r14al expression in rhombomere 4. Furthermore, ppp1r14al is essential for establishment of the earliest hindbrain signaling-center in rhombomere 4 by regulating expression of fgf3.
Title: A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein phosphatase inhibitor activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine phosphatase inhibitor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein phosphatase 1, regulatory (inhibitor) subunit 14Aa

Names: protein phosphatase 1, regulatory (inhibitor) subunit 14A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.