c1qtnf4 C1q and TNF related 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: c1qtnf4provided by ZNC
Official Full Name: C1q and TNF related 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-198
See related: Ensembl:ENSDARG00000024299 AllianceGenome:ZFIN:ZDB-GENE-050417-198
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:112213
Summary: Predicted to be active in extracellular space. Is expressed in brain. Orthologous to human C1QTNF4 (C1q and TNF related 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (38600150..38612284, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (38328889..38362569, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results establish CTRP4 as a novel nutrient-responsive central regulator of food intake and energy balance.
Title: C1q/TNF-related protein 4 (CTRP4) is a unique secreted protein with two tandem C1q domains that functions in the hypothalamus to modulate food intake and body weight.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: complement C1q tumor necrosis factor-related protein 4

Names: C1q and tumor necrosis factor related protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017702.2 → NP_001017702.2 complement C1q tumor necrosis factor-related protein 4 precursor

Status: VALIDATED

Source sequence(s)

CR318601

UniProtKB/TrEMBL

Q566Z3

Related

ENSDARP00000142965.1, ENSDART00000173678.2