ponzr1 plac8 onzin related protein 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ponzr1provided by ZNC
Official Full Name: plac8 onzin related protein 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-070727-1
See related: Ensembl:ENSDARG00000090444 AllianceGenome:ZFIN:ZDB-GENE-070727-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: gb:eh433777; si:dkey-33c9.4
Summary: Acts upstream of or within embryonic viscerocranium morphogenesis; nephron tubule morphogenesis; and pronephric glomerulus morphogenesis. Is expressed in head; intermediate mesoderm; optic stalk; and pronephros. Orthologous to human CNFN (cornifelin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (20344634..20369865)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (20092666..20117897)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer.
Title: Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer.
Data molecularly and functionally characterize one member of an evolutionarily dynamic gene family, plac8 onzin related protein 1 (ponzr1), in the zebrafish.
Title: The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development.

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryonic viscerocranium morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within nephron tubule morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within pronephric glomerulus morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

General protein information

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Preferred Names: plac8 onzin related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001327748.1 → NP_001314677.1 plac8 onzin related protein 1

Status: VALIDATED

Source sequence(s)

EH444076, EH496546

UniProtKB/TrEMBL

A0A8M1P986, E7F147

Related

ENSDARP00000113816.1, ENSDART00000139685.2

Conserved Domains (1) summary

pfam04749
Location:19 → 105

PLAC8; PLAC8 family