si:ch1073-205c8.3 si:ch1073-205c8.3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: si:ch1073-205c8.3provided by ZNC
Official Full Name: si:ch1073-205c8.3provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-1059
See related: Ensembl:ENSDARG00000101521 AllianceGenome:ZFIN:ZDB-GENE-030131-1059
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fb58e05
Summary: Predicted to enable NEDD8 transferase activity. Predicted to be involved in protein neddylation. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including blastomere; central nervous system; eye; otic vesicle; and yolk. Orthologous to human UBE2M (ubiquitin conjugating enzyme E2 M). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

See si:ch1073-205c8.3 in Genome Data Viewer

Location:: chromosome: 19

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (48018797..48023764)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (48357710..48363497)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

G46551 (e-PCR)
- UniSTS:107352

fb58e05.x1 (e-PCR)
- UniSTS:190811

fb58e05 (e-PCR)
- UniSTS:187244

Z9559 (e-PCR)
- UniSTS:38808

fb53b08.x1 (e-PCR)
- UniSTS:190673

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables NEDD8 transferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein neddylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: NEDD8-conjugating enzyme Ubc12

XP_001920670.3

EC 6.3.2.19

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007130.7 Reference GRCz11 Primary Assembly

Range

48018797..48023764

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001920635.9 → XP_001920670.3 NEDD8-conjugating enzyme Ubc12

UniProtKB/TrEMBL

A0A0R4IUU4, A0A8M1QUV9

Related

ENSDARP00000138225.1, ENSDART00000172307.2

Conserved Domains (2) summary

COG5078
Location:28 → 173

COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]

pfam00179
Location:35 → 168

UQ_con; Ubiquitin-conjugating enzyme