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    ap5m1 adaptor related protein complex 5 subunit mu 1 [ Danio rerio (zebrafish) ]

    Gene ID: 553681, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ap5m1provided by ZNC
    Official Full Name
    adaptor related protein complex 5 subunit mu 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-231
    See related
    Ensembl:ENSDARG00000031533 AllianceGenome:ZFIN:ZDB-GENE-050522-231
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:112153
    Summary
    Predicted to be involved in endosomal transport. Predicted to act upstream of or within protein transport. Predicted to be located in membrane. Predicted to be part of AP-type membrane coat adaptor complex. Predicted to be active in cytosol; late endosome; and lysosome. Orthologous to human AP5M1 (adaptor related protein complex 5 subunit mu 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ap5m1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (44441039..44454020)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (44327282..44340255)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488138 Neighboring gene exocyst complex component 5 Neighboring gene N-alpha-acetyltransferase 30, NatC catalytic subunit Neighboring gene solute carrier family 35 member F4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC112153

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    AP-5 complex subunit mu-1
    Names
    adaptor-related protein complex 5, mu 1 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020654.1 → NP_001018490.1  AP-5 complex subunit mu-1

      See identical proteins and their annotated locations for NP_001018490.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095676
      UniProtKB/TrEMBL
      Q502J2
      Conserved Domains (1) summary
      cd09256
      Location:200 → 467
      AP_MuD_MHD; Mu-homology domain (MHD) of a adaptor protein (AP) encoded by mu-2 related death-inducing gene, MuD (also known as MUDENG)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      44441039..44454020
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005158894.4 → XP_005158951.1  AP-5 complex subunit mu-1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B5U6
      Related
      ENSDARP00000117738.1, ENSDART00000142123.2
      Conserved Domains (1) summary
      cd09256
      Location:200 → 484
      AP_MuD_MHD; Mu-homology domain (MHD) of a adaptor protein (AP) encoded by mu-2 related death-inducing gene, MuD (also known as MUDENG)
    Nucleotide Protein
    Heading Accession and Version

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