irf2bp1 interferon regulatory factor 2 binding protein 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: irf2bp1provided by ZNC
Official Full Name: interferon regulatory factor 2 binding protein 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-050420-389
See related: Ensembl:ENSDARG00000005468 AllianceGenome:ZFIN:ZDB-GENE-050420-389
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-223n17.3
Summary: Predicted to enable transcription corepressor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human IRF2BP1 (interferon regulatory factor 2 binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 18

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (46362659..46369675, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (46364641..46371657, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: interferon regulatory factor 2-binding protein 1

Names: IRF-2-binding protein 1; IRF-2BP1

NP_001037819.2

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001044354.2 → NP_001037819.2 interferon regulatory factor 2-binding protein 1

See identical proteins and their annotated locations for NP_001037819.2

Status: PROVISIONAL

Source sequence(s)

BC134860

UniProtKB/Swiss-Prot

A4IG01, Q1LV17

Related

ENSDARP00000026919.8, ENSDART00000018163.9

Conserved Domains (2) summary

pfam11261
Location:13 → 61

IRF-2BP1_2; Interferon regulatory factor 2-binding protein zinc finger

pfam13923
Location:524 → 568

zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)