timm44 translocase of inner mitochondrial membrane 44 homolog (yeast) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: timm44provided by ZNC
Official Full Name: translocase of inner mitochondrial membrane 44 homolog (yeast)provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-145
See related: Ensembl:ENSDARG00000104771 AllianceGenome:ZFIN:ZDB-GENE-030131-145
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7142269; wu:fl70d04; zgc:110764; hm:zehn1275
Summary: Predicted to enable protein-folding chaperone binding activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to act upstream of or within protein transport. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Orthologous to human TIMM44 (translocase of inner mitochondrial membrane 44). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (4447442..4463478)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (3994594..4010630)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc17h01.y1 (e-PCR)
- UniSTS:192836

fc35b02.x1 (e-PCR)
- UniSTS:193622

AI617238 (e-PCR)
- UniSTS:206172

fc36e07.y1 (e-PCR)
- UniSTS:193678

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein-folding chaperone binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein import into mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein import into mitochondrial matrix	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitochondrial import inner membrane translocase subunit TIM44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013507.1 → NP_001013525.1 mitochondrial import inner membrane translocase subunit TIM44

See identical proteins and their annotated locations for NP_001013525.1

Status: PROVISIONAL

Source sequence(s)

BC090431

UniProtKB/TrEMBL

Q5BLH8

Related

ENSDARP00000138201.1, ENSDART00000166768.2

Conserved Domains (3) summary

TIGR00984
Location:66 → 442

3a0801s03tim44; mitochondrial import inner membrane, translocase subunit

pfam04280
Location:297 → 445

Tim44; Tim44-like domain

cl21478
Location:58 → 136

ATP-synt_B; ATP synthase B/B' CF(0)