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    meaf6 MYST/Esa1-associated factor 6 [ Danio rerio (zebrafish) ]

    Gene ID: 445300, updated on 9-Dec-2024

    Summary

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    Official Symbol
    meaf6provided by ZNC
    Official Full Name
    MYST/Esa1-associated factor 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040808-12
    See related
    Ensembl:ENSDARG00000101216 AllianceGenome:ZFIN:ZDB-GENE-040808-12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj63g06; wu:fj63g06; zgc:100869
    Summary
    Predicted to contribute to histone acetyltransferase activity. Predicted to act upstream of or within chromatin organization. Predicted to be located in kinetochore and nucleolus. Predicted to be part of MOZ/MORF histone acetyltransferase complex and NuA4 histone acetyltransferase complex. Orthologous to human MEAF6 (MYST/Esa1 associated factor 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See meaf6 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (4024443..4033042)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (4093601..4102216)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene MAP7 domain containing 1b Neighboring gene uncharacterized LOC100149327 Neighboring gene sperm-tail PG-rich repeat containing 1 Neighboring gene bloodthirsty-related gene family, member 23 Neighboring gene bloodthirsty-related gene family, member 24

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of single-cell transcriptomics in human and Zebrafish oocytes. Can H, et al. BMC Genomics, 2020 Jul 8. PMID 32640983, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    contributes_to histone H3K14 acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    contributes_to histone H4K12 acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    contributes_to histone H4K5 acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    contributes_to histone H4K8 acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of MOZ/MORF histone acetyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of MOZ/MORF histone acetyltransferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of NuA4 histone acetyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of NuA4 histone acetyltransferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of histone acetyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in kinetochore ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    chromatin modification-related protein MEAF6
    Names
    esa1-associated factor 6 homolog
    protein EAF6 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003756.1 → NP_001003756.1  chromatin modification-related protein MEAF6

      See identical proteins and their annotated locations for NP_001003756.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078210
      UniProtKB/Swiss-Prot
      Q6AZD3
      Related
      ENSDARP00000132726.1, ENSDART00000159215.2
      Conserved Domains (1) summary
      pfam09340
      Location:17 → 94
      NuA4; Histone acetyltransferase subunit NuA4

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      4024443..4033042
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005173744.5 → XP_005173801.1  chromatin modification-related protein MEAF6 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IX41, A0A8M2BLF2
      Related
      ENSDARP00000141878.1, ENSDART00000172204.2
      Conserved Domains (1) summary
      pfam09340
      Location:17 → 94
      NuA4; Histone acetyltransferase subunit NuA4
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AZD3.1 GenPept UniProtKB/Swiss-Prot:Q6AZD3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.