snx2 sorting nexin 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: snx2provided by ZNC
Official Full Name: sorting nexin 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-051120-45
See related: AllianceGenome:ZFIN:ZDB-GENE-051120-45
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:123293
Summary: Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in early endosome to Golgi transport. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in early endosome membrane and lamellipodium. Predicted to be part of retromer complex. Predicted to be active in endosome membrane. Orthologous to human SNX2 (sorting nexin 2). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (144091..175648)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (293270..324827)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in early endosome to Golgi transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in early endosome membrane	IEA Inferred from Electronic Annotation more info
is_active_in endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in endosome	IEA Inferred from Electronic Annotation more info
is_active_in endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in lamellipodium	IEA Inferred from Electronic Annotation more info
part_of retromer complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sorting nexin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001037698.1 → NP_001032787.1 sorting nexin-2

See identical proteins and their annotated locations for NP_001032787.1

Status: PROVISIONAL

Source sequence(s)

BC109441

UniProtKB/TrEMBL

Q32LT0

Conserved Domains (3) summary

cd07282
Location:129 → 252

PX_SNX2; The phosphoinositide binding Phox Homology domain of Sorting Nexin 2

cd07664
Location:270 → 503

BAR_SNX2; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 2

pfam03700
Location:33 → 101

Sorting_nexin; Sorting nexin, N-terminal domain