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    K08E7.8 Leucine-rich repeat domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178213, updated on 9-Dec-2024

    Summary

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    Official Symbol
    K08E7.8
    Official Full Name
    Leucine-rich repeat domain-containing protein
    Primary source
    WormBase:WBGene00010675
    Locus tag
    CELE_K08E7.8
    See related
    AllianceGenome:WB:WBGene00010675
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in anal depressor muscle; body wall musculature; pharynx; and reproductive system. Orthologous to human LRRC20 (leucine rich repeat containing 20). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See K08E7.8 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (12585190..12586066, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Mucin-5AC;Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene Myb_DNA-bind_5 domain-containing protein Neighboring gene Cullin-6 Neighboring gene Multidrug resistance protein pgp-1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Leucine-rich repeat domain-containing protein
    NP_001040969.1
    • Confirmed by transcript evidence
    NP_001040970.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12585190..12586066 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047504.6 → NP_001040969.1  Leucine-rich repeat domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040969.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21347
      Conserved Domains (3) summary
      cd00116
      Location:76 → 174
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00031
      Location:50 → 73
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:95 → 153
      LRR_8; Leucine rich repeat

    2. NM_001047505.3 → NP_001040970.1  Leucine-rich repeat domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040970.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2EEN9
      Conserved Domains (3) summary
      cd00116
      Location:42 → 140
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:17 → 39
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:61 → 119
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version

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