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    gly-16 GLYcosylation related [ Caenorhabditis elegans ]

    Gene ID: 173109, updated on 27-Dec-2024

    Summary

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    Official Symbol
    gly-16
    Official Full Name
    GLYcosylation related
    Primary source
    WormBase:WBGene00001641
    Locus tag
    CELE_T15D6.2
    See related
    AllianceGenome:WB:WBGene00001641
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acetylglucosaminyltransferase activity. Predicted to be located in Golgi membrane. Is expressed in seam cell. Human ortholog(s) of this gene implicated in cataract and cataract 13 with adult i phenotype. Orthologous to several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gly-16 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (12379335..12381032, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene B3GNT1, Beta-1,3-N-acetylGucosamiNylTransferase 1, homolog Neighboring gene GLYcosylation related Neighboring gene Hexosyltransferase Neighboring gene Nuclear hormone receptor family member nhr-77

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues. Warren CE, et al. Glycobiology, 2001 Nov. PMID 11744632
    2. Histone deacetylase HDA-4-mediated epigenetic regulation in space-flown C. elegans. Higashitani A, et al. NPJ Microgravity, 2021 Sep 1. PMID 34471121, Free PMC Article
    3. Carbohydrates and glycosylation. Berninsone PM. WormBook, 2006 Dec 18. PMID 18050430, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acetylglucosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GLYcosylation related
    NP_493135.2
    • Product from WormBase gene class gly;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      12379335..12381032 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060734.4 → NP_493135.2  GLYcosylation related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493135.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDP7
      Conserved Domains (1) summary
      pfam02485
      Location:116 → 353
      Branch; Core-2/I-Branching enzyme
    Nucleotide Protein
    Heading Accession and Version

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