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    kin-9 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181098, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kin-9
    Official Full Name
    Protein kinase domain-containing protein
    Primary source
    WormBase:WBGene00002195
    Locus tag
    CELE_F08F1.1
    See related
    AllianceGenome:WB:WBGene00002195
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in intestine; pharynx; and tail. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kin-9 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (8432661..8437350)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The FGFR4 Homolog KIN-9 Regulates Lifespan and Stress Responses in Caenorhabditis elegans. Mallick A, et al. Front Aging, 2022. PMID 35821842, Free PMC Article
    2. Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans. Huang M, et al. Nature, 1994 Feb 3. PMID 7509039
    3. FGF negatively regulates muscle membrane extension in Caenorhabditis elegans. Dixon SJ, et al. Development, 2006 Apr. PMID 16495308
    4. Genomic overview of protein kinases. Manning G. WormBook, 2005 Dec 13. PMID 18050405, Free PMC Article
    5. A global analysis of genetic interactions in Caenorhabditis elegans. Byrne AB, et al. J Biol, 2007. PMID 17897480, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane receptor protein tyrosine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in multicellular organism development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Protein kinase domain-containing protein
    NP_001257058.1
    • Confirmed by transcript evidence
    NP_001359980.1
    • Confirmed by transcript evidence
    NP_001359981.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8432661..8437350
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001270129.4 → NP_001257058.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257058.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F3NWW5
      Conserved Domains (2) summary
      cd00192
      Location:277 → 557
      PTKc; Catalytic domain of Protein Tyrosine Kinases
      pfam08693
      Location:194 → 230
      SKG6; Transmembrane alpha-helix domain

    2. NM_001373393.3 → NP_001359981.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZN4
      Conserved Domains (2) summary
      cd00192
      Location:247 → 527
      PTKc; Catalytic domain of Protein Tyrosine Kinases
      pfam08693
      Location:164 → 200
      SKG6; Transmembrane alpha-helix domain

    3. NM_001373394.2 → NP_001359980.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZN3
      Conserved Domains (2) summary
      cd00192
      Location:110 → 390
      PTKc; Catalytic domain of Protein Tyrosine Kinases
      pfam08693
      Location:27 → 63
      SKG6; Transmembrane alpha-helix domain
    Nucleotide Protein
    Heading Accession and Version

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