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    C17H12.5 Tyrosine-protein phosphatase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182754, updated on 9-Dec-2024

    Summary

    Official Symbol
    C17H12.5
    Official Full Name
    Tyrosine-protein phosphatase domain-containing protein
    Primary source
    WormBase:WBGene00015931
    Locus tag
    CELE_C17H12.5
    See related
    AllianceGenome:WB:WBGene00015931
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See C17H12.5 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (6815911..6817654, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene One cut domain family member Neighboring gene ncRNA Neighboring gene CUB-like domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    General protein information

    Preferred Names
    Tyrosine-protein phosphatase domain-containing protein
    NP_501047.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      6815911..6817654 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068646.3NP_501047.1  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501047.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45079
      Conserved Domains (2) summary
      smart00194
      Location:155408
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cl21483
      Location:193405
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...