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    gcc-2 GRIP and coiled-coil domain-containing protein 2 [ Caenorhabditis elegans ]

    Gene ID: 176378, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gcc-2
    Official Full Name
    GRIP and coiled-coil domain-containing protein 2
    Primary source
    WormBase:WBGene00011503
    Locus tag
    CELE_T05G5.9
    See related
    AllianceGenome:WB:WBGene00011503
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in Golgi apparatus. Orthologous to human GCC2 (GRIP and coiled-coil domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gcc-2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    10
    Sequence:
    Chromosome: III; NC_003281.10 (9757616..9762143, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative enoyl-CoA hydratase, mitochondrial Neighboring gene Vacuolar protein sorting-associated protein 53 homolog Neighboring gene Regulator of microtubule dynamics protein 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein cbp-1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Luo L, et al. Mol Biol Cell, 2011 Jul 15. PMID 21613545, Free PMC Article
    2. The golgin coiled-coil proteins of the Golgi apparatus. Munro S. Cold Spring Harb Perspect Biol, 2011 Jun 1. PMID 21436057, Free PMC Article
    3. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GRIP and coiled-coil domain-containing protein 2
    NP_001022748.1
    • Confirmed by transcript evidence
    NP_001022749.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9757616..9762143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027577.4 → NP_001022748.1  GRIP and coiled-coil domain-containing protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022748.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34562, Q86DA2
      Conserved Domains (1) summary
      smart00755
      Location:589 → 636
      Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245

    2. NM_001027578.5 → NP_001022749.1  GRIP and coiled-coil domain-containing protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022749.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34562
      Conserved Domains (1) summary
      smart00755
      Location:587 → 634
      Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34562.3

    Gene LinkOut

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