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    tmbi-4 Transmembrane BAX inhibitor motif-containing protein 4 [ Caenorhabditis elegans ]

    Gene ID: 181150, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tmbi-4
    Official Full Name
    Transmembrane BAX inhibitor motif-containing protein 4
    Primary source
    WormBase:WBGene00006479
    Locus tag
    CELE_B0563.4
    See related
    AllianceGenome:WB:WBGene00006479
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium channel activity. Predicted to be involved in endoplasmic reticulum unfolded protein response. Predicted to be active in membrane. Orthologous to human TMBIM4 (transmembrane BAX inhibitor motif containing 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tmbi-4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (9150694..9160650)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein;putative G-protein coupled receptor B0563.6 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene putative calcium-binding protein B0563.7 Neighboring gene Tetraspanin Neighboring gene Neuropeptide-Like Protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane BAX inhibitor motif-containing protein 4
    NP_509543.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      9150694..9160650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077142.9 → NP_509543.2  Transmembrane BAX inhibitor motif-containing protein 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509543.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q11079, Q11080
      Conserved Domains (1) summary
      cd10429
      Location:43 → 275
      GAAP_like; Golgi antiapoptotic protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q11080.2

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