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    mfsd-8.3 MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190242, updated on 4-Jan-2025

    Summary

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    Official Symbol
    mfsd-8.3
    Official Full Name
    MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein
    Primary source
    WormBase:WBGene00021814
    Locus tag
    CELE_Y53G8AR.7
    See related
    AllianceGenome:WB:WBGene00021814
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in lysosomal membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Orthologous to human MFSD8 (major facilitator superfamily domain containing 8). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See mfsd-8.3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    11
    Sequence:
    Chromosome: III; NC_003281.10 (3282308..3290205)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene RING-type domain-containing protein Neighboring gene HTH CENPB-type domain-containing protein Neighboring gene Mitochondrial ATP synthase regulatory component factor B Neighboring gene SAP domain-containing protein Neighboring gene RING-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein
    NP_001022903.1
    • Confirmed by transcript evidence
    NP_001380067.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      3282308..3290205
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027732.5 → NP_001022903.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022903.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3G2
      Conserved Domains (1) summary
      cd17326
      Location:48 → 495
      MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

    2. NM_001393304.1 → NP_001380067.1  MFS domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YZM9
      Conserved Domains (1) summary
      cl28910
      Location:1 → 278
      MFS; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version

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