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    che-7 Innexin [ Caenorhabditis elegans ]

    Gene ID: 184979, updated on 9-Dec-2024

    Summary

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    Official Symbol
    che-7
    Official Full Name
    Innexin
    Primary source
    WormBase:WBGene00000488
    Locus tag
    CELE_F26D11.10
    See related
    AllianceGenome:WB:WBGene00000488
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in gap junction and plasma membrane. Is expressed in nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See che-7 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    13
    Sequence:
    Chromosome: V; NC_003283.11 (7961210..7969207, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene C-type lectin domain-containing protein Neighboring gene Coiled-coil domain-containing protein 137 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene PDZ domain-containing protein;Protein Scribble homolog let-413

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans INX-4/Innexin is required for the fine-tuning of temperature orientation in thermotaxis behavior. Tsukamoto S, et al. Genes Cells, 2020 Mar. PMID 31917862, Free PMC Article
    2. Differential processing of a chemosensory cue across life stages sharing the same valence state in Caenorhabditis elegans. Banerjee N, et al. Proc Natl Acad Sci U S A, 2023 May 9. PMID 37126715, Free PMC Article
    3. Aversive Behavior in the Nematode C. elegans Is Modulated by cGMP and a Neuronal Gap Junction Network. Krzyzanowski MC, et al. PLoS Genet, 2016 Jul. PMID 27459302, Free PMC Article
    4. Interactions between innexins UNC-7 and UNC-9 mediate electrical synapse specificity in the Caenorhabditis elegans locomotory nervous system. Starich TA, et al. Neural Dev, 2009 May 11. PMID 19432959, Free PMC Article
    5. A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans. Kaplan JM, et al. Proc Natl Acad Sci U S A, 1993 Mar 15. PMID 8460126, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables gap junction channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in gap junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in gap junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Innexin
    NP_001309632.1
    • Confirmed by transcript evidence
    NP_001309634.1
    • Confirmed by transcript evidence
    NP_001309635.1
    • Confirmed by transcript evidence
    NP_001317771.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7961210..7969207 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001322573.3 → NP_001309635.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A131MBM6
      Conserved Domains (1) summary
      pfam00876
      Location:58 → 421
      Innexin; Innexin

    2. NM_001322572.2 → NP_001309634.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A131MB33
      Conserved Domains (1) summary
      pfam00876
      Location:58 → 421
      Innexin; Innexin

    3. NM_001330873.2 → NP_001317771.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A131MB60

    4. NM_001322574.2 → NP_001309632.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A131MBQ3
      Conserved Domains (1) summary
      pfam00876
      Location:61 → 424
      Innexin; Innexin
    Nucleotide Protein
    Heading Accession and Version

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