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    Y116A8C.30 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [ Caenorhabditis elegans ]

    Gene ID: 178485, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y116A8C.30
    Official Full Name
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Primary source
    WormBase:WBGene00013807
    Locus tag
    CELE_Y116A8C.30
    See related
    AllianceGenome:WB:WBGene00013807
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 10. Orthologous to human NDUFAF2 (NADH:ubiquinone oxidoreductase complex assembly factor 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y116A8C.30 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (17100321..17103715, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ATP synthase mitochondrial F1 complex assembly factor 2;DUF3800 domain-containing protein Neighboring gene Secreted protein Neighboring gene Carbonic anhydrase Neighboring gene Branchpoint-bridging protein Neighboring gene WSN domain-containing protein;protein of unknown function WSN domain-containing protein Neighboring gene Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase E

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial respiratory chain complex I assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial respiratory chain complex I assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    NP_001041016.1
    • Confirmed by transcript evidence
    NP_001255924.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      17100321..17103715 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047551.5 → NP_001041016.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041016.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U2S7

    2. NM_001268995.3 → NP_001255924.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255924.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8MDW0

    RNA

    1. NR_003160.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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