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    tag-266 Golgin subfamily A member 7/ERF4 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175219, updated on 4-Jan-2025

    Summary

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    Official Symbol
    tag-266
    Official Full Name
    Golgin subfamily A member 7/ERF4 domain-containing protein
    Primary source
    WormBase:WBGene00044319
    Locus tag
    CELE_W06E11.5
    See related
    AllianceGenome:WB:WBGene00044319
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Used to study cancer. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to several human genes including CHIC2 (cysteine rich hydrophobic domain 2). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See tag-266 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (638528..640226, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Ribosome maturation protein SBDS Neighboring gene Major sperm protein Neighboring gene RNB domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Golgin subfamily A member 7/ERF4 domain-containing protein
    NP_001022804.1
    • Partially confirmed by transcript evidence
    NP_497227.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      638528..640226 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064826.7 → NP_497227.1  Golgin subfamily A member 7/ERF4 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497227.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23203, Q9NGL6
      Conserved Domains (1) summary
      pfam10256
      Location:59 → 147
      Erf4; Golgin subfamily A member 7/ERF4 family

    2. NM_001027633.4 → NP_001022804.1  Golgin subfamily A member 7/ERF4 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022804.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I7F9
      Conserved Domains (1) summary
      pfam10256
      Location:59 → 115
      Erf4; Golgin subfamily A member 7/ERF4 family
    Nucleotide Protein
    Heading Accession and Version

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