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    tmem-120 Transmembrane protein 120 homolog [ Caenorhabditis elegans ]

    Gene ID: 175305, updated on 2-Nov-2024

    Summary

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    Official Symbol
    tmem-120
    Official Full Name
    Transmembrane protein 120 homolog
    Primary source
    WormBase:WBGene00019716
    Locus tag
    CELE_M01G5.3
    See related
    AllianceGenome:WB:WBGene00019716
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in membrane. Is expressed in body wall musculature; intestine; nervous system; and rectal gland cell. Orthologous to human TMEM120A (transmembrane protein 120A) and TMEM120B (transmembrane protein 120B). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See tmem-120 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (1509266..1517993, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Casc1_N domain-containing protein Neighboring gene SAM domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Sodium-dependent acetylcholine transporter Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transmembrane protein 120A (TMEM-120A/TACAN) coordinates with PIEZO channel during Caenorhabditis elegans reproductive regulation. Bai X, et al. G3 (Bethesda), 2023 Dec 29. PMID 38051962, Free PMC Article
    2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane protein 120 homolog
    NP_001370801.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1509266..1517993 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001384029.2 → NP_001370801.1  Transmembrane protein 120 homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76687
      Conserved Domains (1) summary
      pfam07851
      Location:9 → 339
      TMPIT; TMPIT-like protein
    Nucleotide Protein
    Heading Accession and Version

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