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    drd-50 ShKT domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177176, updated on 9-Dec-2024

    Summary

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    Official Symbol
    drd-50
    Official Full Name
    ShKT domain-containing protein
    Primary source
    WormBase:WBGene00018643
    Locus tag
    CELE_F49F1.1
    See related
    AllianceGenome:WB:WBGene00018643
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to Gram-positive bacterium and innate immune response. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See drd-50 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (4117732..4119179)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Glycine Rich Secreted Protein Neighboring gene pseudo Neighboring gene ShKT domain-containing protein Neighboring gene ShKT domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. Nandakumar M, et al. PLoS Genet, 2008 Nov. PMID 19023415, Free PMC Article
    2. Regulation of fatty acid desaturase- and immunity gene-expression by mbk-1/DYRK1A in Caenorhabditis elegans. Mack HID, et al. BMC Genomics, 2022 Jan 4. PMID 34983389, Free PMC Article
    3. Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum. O'Rourke D, et al. Genome Res, 2006 Aug. PMID 16809667, Free PMC Article
    4. Identifying evolutionarily conserved genes in the dietary restriction response using bioinformatics and subsequent testing in Caenorhabditis elegans. Ludewig AH, et al. Genes Nutr, 2014 Jan. PMID 24311442, Free PMC Article
    5. Improved Biocompatibility of Amino-Functionalized Graphene Oxide in Caenorhabditis elegans. Rive C, et al. Small, 2019 Nov. PMID 31576668

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in defense response to Gram-positive bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in innate immune response HEP PubMed 
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ShKT domain-containing protein
    NP_500485.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      4117732..4119179
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068084.5 → NP_500485.1  ShKT domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500485.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GZE5
    Nucleotide Protein
    Heading Accession and Version

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