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    lro-1 Lysosome-Related Organelle protein [ Caenorhabditis elegans ]

    Gene ID: 180901, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lro-1
    Official Full Name
    Lysosome-Related Organelle protein
    Primary source
    WormBase:WBGene00021048
    Locus tag
    CELE_W05H9.1
    See related
    AllianceGenome:WB:WBGene00021048
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lro-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (6272089..6273768)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ANK_REP_REGION domain-containing protein Neighboring gene Dynein heavy chain 7, axonemal Neighboring gene ncRNA Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantitative Profiling Identifies Potential Regulatory Proteins Involved in Development from Dauer Stage to L4 Stage in Caenorhabditis elegans. Kim S, et al. J Proteome Res, 2016 Feb 5. PMID 26751275
    2. Mass spectrometric proteome analysis for profiling temperature-dependent changes of protein expression in wild-type Caenorhabditis elegans. Mádi A, et al. Proteomics, 2003 Aug. PMID 12923778
    3. Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. Gottschalk A, et al. EMBO J, 2005 Jul 20. PMID 15990870, Free PMC Article
    4. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
    5. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lysosome-Related Organelle protein
    NP_001263957.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class lro
    NP_509050.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class lro

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6272089..6273768
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076649.6 → NP_509050.1  Lysosome-Related Organelle protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509050.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23179
      Conserved Domains (3) summary
      pfam01442
      Location:116 → 274
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cd16269
      Location:202 → 213
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:146 → 228
      GBP_C; Guanylate-binding protein, C-terminal domain

    2. NM_001277028.4 → NP_001263957.1  Lysosome-Related Organelle protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263957.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      L8E833
      Conserved Domains (3) summary
      pfam01442
      Location:116 → 281
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cd16269
      Location:202 → 213
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:146 → 228
      GBP_C; Guanylate-binding protein, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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